(IUPAC) International Conference on Biodiversity and Natural Products (ICOB-6 and ISCNP-26) PEI 2008

Conference Venue - Delta Prince Edward Hotel

Charlottetown, Prince Edward Island, Canada, is home to The Delta Prince Edward. The Delta Prince Edward is conveniently located, affording stunning water views from 70% of the guestrooms. The remainder of the rooms offer a picturesque glimpse of colonial-flavoured Olde Charlottetown, with its wide tree-lined streets and spectacular examples of Victorian architecture.

Click here to visit their web site and access their special conference rates.

Charlottetown, Prince Edward Island

The City of Charlottetown is a flourishing community of over 30,000 people located on the south shore of Prince Edward Island. Charlottetown is the capital city of Prince Edward Island, and is called "Canada's Birthplace" after the historic 1864 Charlottetown Conference which led to Confederation. Charlottetown is rich in history and culture, and is the home of the University of Prince Edward Island and Holland College. For more information on the city of Charlottetown please visit www.city.charlottetown.pe.ca

Outline of Scientific Program

Sunday, July 13

8:00 - 5:00	Registration - Delta Prince Edward lobby (Registration and Info. Desk open daily during sessions)
5:00 - 8:00	Opening Reception - Peake’s Quay Restaurant Peake’s Quay is a 2 minute walk from the Delta Prince Edward and is immediately to the east (right in the map below) of the Delta hotel. Please make sure that you bring your conference name badge (with beverage tickets) which is required for admission. A light meal will be provided.

Monday, July 14 - Edward / Island Rooms

7:30 - 8:00	Continental Breakfast Ballroom Foyer
	WELCOME
8:00 - 8:20	Welcome remarks from Russell Kerr (Conference Chair) Hon. Robert Ghiz (Premier of Prince Edward Island) Michael Mayne (Deputy Minister, Innovation and Advanced Learning)
8:20 - 8:30	Welcome remarks from Mary Garson (IUPAC representative)
	ISOLATION AND STRUCTURE ELUCIDATION (Chair - Russell Kerr)
8:30 - 9:10	Raymond Andersen (University of British Columbia) "Bioactive Marine Natural Products that are Potential Drug Leads and Cell Biology Tools"
9:10 - 9:40	Nobuhiro Fusetani (Hokkaido University) "Bioactive Metabolites from Marine Organisms"
9:40 - 10:10	Jeffrey Wright (University of North Carolina, Wilmington) "Poisons, Peptides and Polyethers: Building a Diverse, Complex Library of Natural Products"
10:10 - 10:40	Coffee break - Ballroom Foyer
	(Chair - Mary Garson)
10:40 - 11:10	Jun’ichi Kobayashi (Hokkaido University) "Chemistry and Biology of Okinawan Marine Natural Products"
	BIOSYNTHESIS OF NATURAL PRODUCTS 1
11:10 - 11:40	John Vederas (University of Alberta) "Biosynthesis of Lovastatin by an AIterative Type I Polyketide Synthase"
11:40 - 12:10	Dale Poulter (University of Utah) "Structural Diversity in the Isoprenoid Pathway: Constructing Carbon Skeletons"
12:10 -1:50	LUNCH - Prince Room
	SPECTROSCOPY (Chair - Jeffrey Wright)
1:50 - 2:20	Michio Murata (Osaka University) "Ion Channel Complex of Antibiotics as Viewed by NMR"
2:20 - 2:50	Murray Munro (University of Canterbury) "The Role of NMR Spectroscopy as a Dereplication Tool"
2:50 - 3:20	Kimberly Colson (Bruker BioSpin Corp.) "Automated Natural Product Extract Screening Using 1H NMR"
3:30 - 5:30	Poster Session 1 - Prince Room

Tuesday, July 15 - Edward / Island Rooms

8:00 - 8:30	Continental Breakfast - Ballroom Foyer
	BIOSYNTHESIS OF NATURAL PRODUCTS 2 (Chair - Bob Chapman)
8:30 - 8:50	Mary Garson (The University of Queensland) "Stereochemistry and Medicinal Natural Products: Pitfalls and Progress"
8:50 - 9:10	David Jakeman (Dalhousie University) "Probing Structure-activity Relationships of the Jadomycins by Redirecting Biosynthesis in Streptomyceces venezuelae ISP5230"
9:10 - 9:30	Nathan Magarvey (McMaster University) "Gatekeeping vs. Promiscuity in the Early Stages of the Andrimid Biosynthetic Assembly Line"
9:30 - 9:50	Yansheng Zhang (Plant Biotechnology Institute, National Research Council) "Double Bond Reduction in Artemisinin Biosynthesis"
	SYNTHESIS 1
9:50 - 10:10	Yukari Fujimoto (Osaka University) "Synthesis of Immunostimulatory Peptidoglycan Fragments Recognized by the Intracellular Receptors"
10:10 - 10:40	Coffee break - Ballroom Foyer
10:40 - 11:00	Anuchit Plubrukarn (Prince of Songkla University) "Structure-activity Relationships of Antitubular Scalarens" Heteronemin Revisited"
11:00 - 11:20	Hiroshi Imagawa (Tokushima Bunri University) "Development of a Hg(OTf)2-catalyzed Reaction and Application to the Synthesis of Thallusin"
11:20 -11:40	Rao Manam (Nereus Pharmaceuticals) "Synthesis of Highly Potent Non-halogen Leaving Group Analogs of NPI-0052 (Salinosporoamide A)"
11:40 - 12:00	Naoki Kanoh (Tohoku University, RIKEN) "Photo-generated Carbene as a Chemical Handle for Functionalizing Small Molecules"
12:00 - 1:40	LUNCH - Prince Room
	ISOLATION OF NEW BIOACTIVE NATURAL PRODUCTS
1:40 - 2:00	William Kem (University of Florida) "Hoplonemertine Pyridine Alkaloids: New Structures and Biosynthetic Considerations"
2:00 - 2:20	Olivier Thomas (Université de Nice-Sophia Antipolis) "New 3-Alkylpyridiniums from Haplosclerida Sponges: Isolation, Chemical Synthesis, and Biosynthetic Considerations"
2:20 - 2:40	David Overy (Merck Research Laboratories) "Characterization of Fusarium larvarum Strains Producing the Novel Antifungal, Polyadenosine Polymerase Inhibitors, Parnafungins A and B"
2:40 - 3:00	Kirk Gustafson (National Cancer Institute) "New Natural Product Inhibitors of the Multi-drug Transporter ABCG2"
3:00 - 3:20	Shawna MacKinnon (Institute for Marine Biosciences, National Research Council of Canada) "The Isolation of a Novel Subclass of Spirolides from the Dinoflagellate Alexandrium osterfeldii"
3:30 - 5:30	Poster Session 2 - Prince Room

Wednesday, July 16 - Edward / Island Rooms

8:00 - 8:30	Continental Breakfast - Ballroom Foyer
	ENGINEERED BIOSYNTHESIS (Chair - Coran Watanabe)
8:30 - 9:10	Peter Leadlay (University of Cambridge) "Analyzing and Altering Stereochemical Control on Modular Polyketide Synthases"
9:10 - 9:40	Barrie Wilkinson (Biotica Technology Ltd.) "Hsp90 Inhibitor Optimization by Biosynthetic Engineering"
	NATURAL PRODUCTS AS ANTICANCER LEADS
9:40 - 10:10	Douglas Kinghorn (The Ohio State University) "Discovery of Anticancer Agents of Diverse Natural Origin"
10:10 - 10:40	Coffee break - Ballroom Foyer
10:40 - 11:10	Chris Ireland (University of Utah) (Chair - Kirk Gustafson) "Marine Natural Product Antitumor Agents"
	SYNTHESIS 2
11:10 - 11:40	Stephen Hanessian (Université de Montréal) "Structure-based Synthesis: from Natural Products to Drug Prototypes"
11:40 - 12:10	Tadeusz Molinski (University of California, San Diego) "Synthetic Advantages in Marine Natural Products Studies"
12:10	LUNCH Pick up boxed lunch in Ballroom Foyer Afternoon open for excursions & site seeing.

Thursday, July 17 - Session A - Prince Room

8:00-8:30	Continental Breakfast - Ballroom Foyer
	BIOMEDICAL APPLICATIONS OF NATURAL PRODUCTS (Chair – Junzeng Zhang)
8:30-8:50	Qi Jia (Unigen Pharmaceuticals) “Solid Tumor Anticancer Drugs from a Medicinal Plant Library”
8:50-9:10	Marianna Kulka (National Research Council, Institute of Nutrisciences and Health) “In vivo and in vitro Human and Animal Models for Testing of Effective Therapies of Asthma and Allergic Diseases”
9:10-9:30	David Konkin (University of Saskatchewan, and Plant Biotechnology Institute, NRC) “Cytoprotective Phthalides from Ligusticum porteri”
9:30-9:50	Mahmood Ameen Abdulla (University of Malaya) “Evaluation of Anti-ulcer Activity of Selected Malaysian Medicinal Plants Against Ethanol-induced Gastric Mucosal Injury in Rats”
9:50-10:10	Nilesh Kumar Sharma (Indian Institute of Technology Roorkee) “Saponin Enriched Fraction from Aegle marmelos and their Modulatory Effects on Lipid Peroxidation”
10:10-10:40	Coffee break - Ballroom Foyer
10:40-11:00	Jim Johnston (National Research Council, Institute of Nutrisciences and Health) “An Astrocyte-Neuron Coculture System to Evaluate the Neuroprotective Activities of Natural Products”
11:00-11:20	Athar Ata (University of Winnepeg) “GST and AchE Inhibiting Natural Products from Medicinally Important Plants”
11:20-11:40	Jahromi Farboodniay (Bioconversion and Environmental Research Institute FSTP) “Antihyperglycemic Activity of Trans-stilbenoids from Polygonum hyrcanicum”
11:40-12:00	Agnes Rimando (U.S. Department of Agriculture) “Methylation of Resveratrol by a Sorghum O-methyltransferase Produces Pterostilbene in planta”
12:00-1:40	LUNCH - Edward Room
1:40-2:00	Norber Mbahin (Icipe-African Insect Science for Food and Health) “Biology of the Wild Silkmoth Anaphe panda (Boisduval) in the Kakamega Forest of Western Kenya”
	NEW METHODS IN NATURAL PRODUCTS CHEMISTRY
2:00-2:20	Anatoly Belostotskii (Bar-Ilan University) “A New Powerful Tool in Structural Studies of Natural Products: Calculated Chemical Shifts”
2:20-2:40	Meghal Desai (S.V. National Institute of Technology) “Microwave-Assisted Extraction of Natural Organic Compounds from Aromatic Plants”
5:30	Conference Banquet: Buses will leave the Delta Hotel at 5:30 pm (and the UPEI residence at 5:40) for a 60 min scenic drive to Park Corner Beach for the Conference Banquet. Since the banquet is on a beach, we suggest that casual clothing is most appropriate.

Thursday, July 17 - Session B - Island Room

8:00-8:30	Continental Breakfast - Ballroom Foyer
	MARINE NATURAL PRODUCTS (Chair – Brad Haltli)
8:30-8:50	Prabhu Dutt Mishra (Piramal Life Sciences Ltd.) “Novel Antibacterial Compound from Sponge Associated Bacteria”
8:50-9:10	Masashi Tsuda (Kochi University) “Iriomotelides, a Series of Cytotoxic Macrolides from Marine Benthic Amphidinium dinoflagellate”
9:10-9:30	Thomas Brueck (Florida Atlantic University) “Potential Applications of Marine Microorganisms in the Development of Third Generation Bioproducts”
9:30-9:50	Dovi Kelman (Tel Aviv University and University of Prince Edward Island) “Chemical Warfare in the Sea: the Search for Antibiotics from Red Sea Corals and Sponges”
9:50-10:10	Mohamed Mehiri (Universite de Nice-Sophia Antipolis) “Biomimetic and Total Synthesis of New Alkaloids from Parazoanthus axinellae”
10:10-10:40	Coffee break - Ballroom Foyer
10:40-11:00	Fabrice Berrue (University of Prince Edward Island) “Chemical Investigation of the Gorgonian Erythropodium caribaeorum and its Associated Microbial Community”
	PLANT NATURAL PRODUCTS
11:00-11:20	Sue-Joan Chang (National Cheng Kung University) “Discovery of Functional Extracts from Toonia sinensis Leaves by Proteomics”
11:20-11:40	Minoru Ueda (Tohoku University) “(-)-Eucomic acid, a Chemical Factor Controlling the Nycyinastic Leaf-Movement of Leguminous Model Plant”
11:40-12:00	Yoko Nakamura (Tohoku University) “Enantia-Differential Approach to the Target Protein of Leaf-Closing Factor”
12:00-1:40	LUNCH - Edward Room
1:40-2:00	Noboru Takada (Hirosaki University) “Jasmonates Accelerate Senescence Induced by Abscisic Acid“
2:00-2:20	Rehana Ifzal (HEJ Research Institute of Chemistry) “New Epoxydammarane Triterpenes from Salvia santolinifolia”
2:20-2:40	Maria Fatima da Silva (Universidade Federal de Sao Carlos) “Inhibition of Photophosphorylation and Electron Transport Chain in Thylakoids by Natural products from Rutaceae, Meliaceae Families and Fungus Botryosphaeria rhodina“
5:30	Conference Banquet: Buses will leave the Delta Hotel at 5:30 pm (and the UPEI residence at 5:40) for a 60 min scenic drive to Park Corner Beach for the Conference Banquet. Since the banquet is on a beach, we suggest that casual clothing is most appropriate.

Friday, July 18 - Edward and Island Rooms

8:00-8:30	Continental Breakfast - Ballroom Foyer
	ROYAL SOCIETY OF CHEMISTRY’S “NATURAL PRODUCT REPORTS” LECTURE AWARD (Chair – Daisuke Uemura)
8:30-9:10	Jason Micklefield (The University of Manchester) “Biosynthetic Engineering of Nonribosomal Lipopeptides”
	CHEMICAL ECOLOGY (Chair – William Kem)
9:10-9:50	Daisuke Uemura (Keio University and Nagoya University) “Recent Aspects of Chemical Ecology”
9:50-10:20	Jorg Degenhardt (Max Plank Institute for Chemical Ecology) “The Roles of Volatile Terpenes in Plant Defense”
10:20-10:50	Coffee break
	METABOLOMICS & GENOMICS
10:50-11:20	Young Choi (Institute of Biology Leiden) “Biodiversity and Metabolomics: A Perfect Match”
11:20-11:50	Markus Nett (University of California, San Diego) “Harnessing Bacterial Genetics to the Drug Discovery Process”
11:50-12:10	Russell Kerr - Student Poster Award Presentations Mary Garson - ICOB-7 & ISCNP-27 Russell Kerr - Closing Remarks
12:10-1:30	LUNCH - Prince Room

Networking Events / Social Program

We have some exciting networking events planned for our delegates including a foot tapping, seafood lovers reception and an On the Beach seaside barbeque!

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